The mitotic cycle and cell population control
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چکیده
منابع مشابه
The mitotic cycle and cell population control.
There is a danger, in the study of the mechanisms of control of mitosis, of oversimplifying the problems. This is particularly so in attempts to extract controlling substances from tissues where the procedures used may take no account of the structural heterogeneity of the system. It has to be recognized that in many tissues one will be dealing with a number of subpopulations, related to each o...
متن کاملExpanding the role of HsEg5 within the mitotic and post-mitotic phases of the cell cycle.
The BimC family of kinesin like proteins are involved in spindle dynamics in a wide variety of organisms. The human member of this family, HsEg5, has been implicated in centrosome separation during prophase/prometaphase and in the organization of in vitro mitotic asters. HsEg5 displays a complex distribution during mitosis, associating with the centrosomes, spindle microtubules, specific region...
متن کاملColcemid and the mitotic cycle.
The precise segregation of replicated chromosomes to daughter cells during mitosis depends on the formation of a bipolar spindle composed primarily of microtubules (MTs). Since MTs are highly dynamic structures whose spatial organization is critical for proper spindle function, physical and chemical agents that interfere with MT behavior invariably disrupt mitosis. Perhaps the most notable of t...
متن کاملThe Ultrastructure of a Mammalian Cell during the Mitotic Cycle
With a technique of preselecting the mitotic cell in the living state for subsequent electron microscopy, it has been possible to examine the ultrastructure of the various stages of mitosis with greater precision than has been reported previously. The early dissolution of the nuclear envelope has been found to be preceded by a marked undulation of this structure within the nuclear "hof." This u...
متن کاملControl of Cell Progression through the Mitotic Cycle by Carbohydrate Provision
A stationary phase in the root meristem of excised pea roots was established by prolonged carbohydrate deprivation in sterile culture medium. When the stationary phase had been established, cells that had collected in the G1 period of the mitotic cycle were induced to enter the S stage by subjection to relatively short intervals of carbohydrate provision (sucrose spurts). Progression and cycle ...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1974
ISSN: 0021-9746
DOI: 10.1136/jcp.s3-7.1.19